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Sebastian - Epilepsy (Uruguay) Posted on June 20, 2013

Author Julia Views Posted at 2014/07/10

Name: Sebastian Daniel Miranda

Sex: Male

Country: Uruguay

Age: 7 years

Diagnoses: 1.Cerebral palsy, 2. Epilepsy

Admission Date: 2013-05-11

Days Admitted to the Hospital: 29

Medical History:

The patient was adopted by his parents the second day after birth. The parents found the patient's fonticulus was bigger than a normal baby. So he was sent to a local hospital and was diagnosed with hydrocephalus. He received ventricular shunt surgery 3 times. The patient suffered from an epileptic seizure when he was 1 year old. There was no obvious cause. The attack form was not clear. He didn't receive medication for treatment. The epilepsy attacks increased gradually. The patient started taking antiepileptic drugs for treatment. The times of epileptic seizure was reduced obviously. The attack times are about 1-2 times each year. The patient presented with intelligence developmental delay, speech developmental delay and motor developmental delay. With some assistance, the patient could walk, but the walking gait was abnormal. His bilateral lower limbs would bend when he walked, he didn't receive other therapy. Before treatment, the patient could say "Daddy" "Mama" and the simple words. With some assistance, the patient could walk, but the waking gait was abnormal. Both lower limbs flexion, distort trunk. He had poor ability to finish instructions. He could crawl or sit by himself. His mood was more exciting. His attention was absent.

Nervous System Examination:

Sebastian Daniel Miranda was alert and had a speech disorder. He could only say simple words, such as "daddy", "mama". He knew few words and could only communicate with others simply. He couldn't cooperate with the examination of orientation, memory or calculation. He had obvious salivation. His mood obviously was hyper-excitability and hyperactivity. Both pupils were equal in size and round, the diameter was about 4.5mms. Both pupils were sensitive to light stimuli. The movement of the eyeballs was flexible and had slight nystagmus. The forehead wrinkle pattern was symmetrical. The nasolabial sulcus was equal in depth. He was unable to cooperate with the examination of cranial nerves. There was movement disturbance of both lower limbs. He could walk with some assistance, but the walking gait was abnormal. Bilateral knee joints and hip joints would bend when he walked. The distance of both feet was wider than normal. His heels couldn't touch the floor when he walks or stands. The trunk twist was larger when he walked. He could crawl and maintain sitting position by himself. The crawling speed was quick. The muscle strength of the trunk was weak when he was in the sitting position. He was unable to stand up from a squat position. He couldn't cooperate with the examination of muscle strength. The muscle tone of the four limbs was normal. Bilateral knee joints and ankle joints was tighter than normal. The tendon reflex of the four limbs was normal. The abdominal reflexes were normal. Bilateral Hoffmann sign was negative. Bilateral sucking reflex was negative. Bilateral palm jaw reflexes were negative. The jaw reflex was negative. Bilateral Babinski sign was negative. He couldn't cooperate with sensory system examination. He also couldn't cooperate with the coordinate movement examination. The meningeal irritation was negative.

Treatment:

After admission, Sebastian Daniel Miranda received the relevant examinations and he was diagnosed with Cerebral palsy and Epilepsy. The patient received treatment to improve the blood circulation in order to increase the blood supply to the damaged nerves and to nourish the neurons. He also received treatment for nerve regeneration and neural repair. This was combined with neurological rehabilitation treatment.

Post Treatment:

The patient has quicker growth and development. The weight increased 1Kg. He has more language and less salivation. He has better comprehension and cooperation with others. The degree of hyper-excitability is reduced. The Hyperactivity is reduced. With some assistance, the patient has better walking gait than before. The left lower limb is significantly straighter than before when he walks. The buckling degree of knee joints and hip joints are reduced obviously. The distance of both feet is reduced when he walks. His heels can touch the floor when he walks. The support strength of the back and waist are improved in the sitting position. With a slight assist, the patient can stand up by himself.

 

Sebastian's family member email to us:

Date: 2013-06-26

Hi Dear Dr Wu, Dr Zhao and Lisa.!!

It's a pleasure to write and keep in touch with all of you.!!

We promise to you that we will send a report and informer about the functional lever.It's two weeks that we return home and we send it .!!

Sebastion is going better everyday!! He do the exercises with the therapist and the therapist said that he stand more strong holding with one hand and his legs are very strong too.!!

Last week he increased his weight.! Now is 22,5 kg.!!

Please! tell about the medicine,especially DPA if we give more tablets because o his weight.!

Another good news is he hasn't got a convulsion and he has a very good sense of humour because he always smile.!

He paints with colours since last week and plays more with all kind of toys,he enjoys playing.!

We are very happy because of his progress.!We know he will be better and better for the next weeks and months.!!Lots of people see the good changes that Sebastian has got.!

All of you are very special and you are very professional.!!Please send some greetings to the nurses.I will send some pictures that we took with them.!

Thanks you for everything you do and we keep in touch.!!

Best Regards.!

Jorge Pablo

Date: 2013-07-04

Hi Dear Dr!

Sebastian is good,he increased his weight now.When we return from the Hospital he was 21k and now he has 24k!!

Next week we will take another blood test and will send to you.

He is doing exercises everyday and he is very happy always too.! All the people see the changes in his life.!

I wish you all  are very well and we keep in touch.!

Best Regards

Jorge Pablo

Date: 2013-07-14

Hi ! Dear Dr Zhao!

It´s a pleasure to write to you again.!

I'm sending now a new blood test.Sebastian is good and continues eating everything.He increased his weight.He plays more and do the excercises and he is learning to paint with colours.

Please! compare the last blood test with this.

Everyday all the people ask us about the treatment and about the Medical Center.We are so happy to give a testimony about of your professional service.!!

You must know now  that we are working hard and making arrangements  to go for second time next year.!!

Thanks you for everything.!

Best Regards for you and all the staff of the Hospital.!!

Jorge Pablo

Some picutre from Sebastian:

How is going everything?

We are so happy to write to you again and keep in touch with all of you.!!

Here I`m sending another blood test of Sebastian.

He is growing very good,eats  more and more and alone.!!!!

Now we ask you about the medicine Silymarine because it´s finished and we want to know if this medicine is in our country,in Uruguay or if we must buy to you.And another question is about the rest of the medicine;what we do when it end?

We are preparing everything and make the arrangements to go next year again to your medical center.We felt at home and we want to return.!!!!!!!!!!Thanks again for all you do.!!!!

We are waiting another instructions from you.!!

Best Regards and we love all of you.!!

Have a nice day from Uruguay.!!!!

Jorge Pablo,Claudia and Sebastian

Sun, 6 Oct 2013

My Dear Dr Wu and All the Staff of Medical Center.!!

Hi!!!!How is going?

Me and my family are very good and Sebastion is ver good too.

He incresead 1K more this week.Now is in 27 k.!!!!!

All of us have saw the changes and the behavior of Sebastian.!!

I will write to you next week again and I will send new pictures of Sebastion.!!

Best Reoards from Jorge Pablo,Claudia and Sebastion

Have a nice weekend and a great week from Uruguay.!!!

We love all of you

Jorge Pablo

Date: 2013-12-17

Hi Dear Dr ,how is going everything?

It's a pleasure to write to you and keep in touch.!!

We are so happy and expecting a lot,  the arrive of the second week of April 2014 to see all of you again.

Sebastian is good, feels happy , increase his weight,eat a lot and do more things than before to go to China, but sometimes,not always, he feels like in another world  because reacts and acts differently. 

We are giving medicine in the correct time,doing exercises everyday and plays with him all the time and plays with all of his toys.

Today he had a bad seizure that lasted 5 minutes. The last was in June.

Anyway, we have seen good changes in their behavior since returning home and we noticed them, and many people have seen the changes too.

Hope we'll see you very soon.

Sincerelly,

Jorge Pablo,Claudia and Sebastion Miranda

The second treatment:

Sebastian Daniel Miranda Iglesias is an 8-years-old boy. He was diagnosed with 1.Cerebral palsy, 2. Epilepsy. The patient received one therapy in our hospital in May 2013. After therapy, the patient had quick growth and development. His weight was increased too. He could say more words. He had better comprehension and cooperation with others. His emotion became better than before. His hyperactivity had reduced. With some assistance, the patient had better walking gait than before. His heels could touch floor when he walks. The support strength of back and waist had improved in sitting position. With a slight assistance, the patient could stand up by himself from squatting position.

 

Admission PE:

Bp: 99/66mmHg; Hr: 95/min. Height: 127cms, weight: 28kgs. The skin and mucosa were normal with no hemorrhaging spots or yellow stains. The respiratory sounds in both lungs were clear, with no dry or moist rales. Through auscultation, the heart sound was strong. He had sinus arrhythmia. There was no obvious murmur in the auscultatory valve areas. The abdomen was smooth, with no pressing pain or rebound tenderness. The liver and spleen were not palpable under the ribs.

Nervous System Examination:

Sebastian was alert and had a speech disorder. He could only say simple words, such as "daddy", "mama" and "Hello". He knew few words and only could communicate with others simply. He had good ability of comprehension and cooperation. He couldn't cooperate with the examination of orientation or memory. His mood obviously was hyperexcitability and hyperactivity state. Both pupils were equal in size and round, the diameter was about 4.5mms. Both pupils were sensitive to light stimuli. The movement of eyeballs was flexible and had slight nystagmus. The forehead wrinkle pattern was symmetrical. The nasolabial sulcus was equal in depth. He was unable to cooperate with the examination of cranial nerves. There was movement disturbance of both lower limbs. He could walk with some assistance, but the walking gait was abnormal. Bilateral knee joints and hip joints would bend when he walks. The distance of both feet was wider than normal. His heels partly touched the floor when he walks or stands. The trunk twisted when he walks. He could crawl and maintain sitting position by himself. The crawling speed was quick. The muscle strength of trunk was weak when he was in the sitting position. The muscle strength was ok, when he stands up from squat position. The activity of both hands was flexible. He was able to open or close door, turn on or off TV, drink water or other daily life activity. He couldn't cooperate with the examination of muscle strength. The muscle tone of his four limbs was normal. Bilateral knee joints and ankle joints was tighter than normal. The tendon reflex of his four limbs was normal.  The abdominal reflexes were normal. Bilateral Hoffmann sign was negative. Bilateral sucking reflex was negative. Bilateral palm jaw reflexes were negative. The jaw reflex was negative. Bilateral Babinski sign was negative. He couldn't cooperate with sensory system examination. He also couldn't cooperate with the coordinate movement examination. The meningeal irritation was negative. The test showed abnormal liver function, the glutamic-pyruvic transaminase was higher than normal.

Treatment:

After admission, Sebastian received the relevant examinations and he was diagnosed with Cerebral palsy, Epilepsy and Abnormal liver function. The patient received treatment for nerve regeneration and to activate stem cells in the body. He received treatment to improve the blood circulation in order to increase the blood supply to the damaged nerves and to nourish the neurons. He also received treatment to protect liver. This was combined with neurological rehabilitation treatment.

Post Treatment:

The patient's sprit and mood are more stable than before. There is no epileptic seizure. The neurological function has improved. Cognitive functional aspects: his concentration or attention is better. He likes littering before the treatment and after treatment the condition is reduced. His speech is clearer than before, and he has gained more vocabulary. He can greet someone actively. He has more communication with others now. He can understand and cooperate with others better. He has a more sensitive reaction to painful stimuli. Sports: the involuntary movement of eyeballs is alleviated. He has eye contact with others. The muscle strength in his waist, back and both lower limbs have increased. The coordination has improved. With some assistance, the patient can go up and descend stairs more easily, and the action is more standard. The activity tolerance has increased obviously. He used obvious less antiepileptic drug. The liver function has restore to normal level.

Date: 2014-05-30

Hi Lisa!!!

My Dear Friend in China!!! Our Friend!!!

How are you? We are fine!!! So I decide to write and send to you this picture of Sebastian drinking "mate" in the morning.!!! Now it's so cold here,and we take care with him.

The next e-mail will be longer than this but I want to send it now.

Best Regards to you from Uruguay and we really love you and all the staff of the hospital!!!

Have a nice day always!!!!

Date: 2014-06-14

Hello Our Dear Family in Beijing.!!!

How are you?I imagine that in your beautiful city is summer now,and here is very cold.!!!We are taking care with Sebastian with the weather,so don't worry about it.

We are fine and happy to write to you.!!!We are sending the first test blood of Sebastian and pictures of his exercises.

Please, try to indicate what we must do and correct with the blood test.

Every monday,tuesday,wednesday and friday we take Sebastiian to do exercises.We show the indications of the exercises plan that you gave us.We have seen that Sebastian has good attitude to do the exercises and the therapist works hard especially with the right leg.!!!  And has the look more fixed.

The therapist is from Cuba and we talk everyday about stem cells.He needs to take his wife for a treatment with stem cells because she lost her memory.He believes and trust in the treatment and recognize that is the only way to obtain a better qualify of life.He will help us with Sebastian and have a goal to work hard for the next 3 months.!!!

I will be giving weekly report !!!

 Is our commitment.!!!

Remember,all of you are our family and we are in our hearts.!!!

Thank very much for everything.!!!

We really love you.!!!

Best Regards from Uruguay

Jorge Pablo,Claudia and Sebastian

Date: 2014-06-27

Hello My Dear Friends in Beijing and Our Nice Friends.!!!

I´m very happy to write to you Dear Lisa and The Staff of the Hospital.

Here, different pictures of SebastiAn in different times.One of these photos was in his 9 birthday on May 15.

Another picture with the flag of Uruguay,very happy in bed watching tv,enjoying the World Cup.I´m finally attaching the recent blood test that you requested again.

Please,tell us what must do and how to improve the values.We bring him everyday the medicine in the list that you gave us,so we respect it.

I talk everyday about Stem Cells with a lot of people.I want to prepare a meeting with future pacient.

SebastiAn is doing excercises with a good attitude but I have a question.: sometimes bites his hand as nervous and tightened strong teeth, it is because of the results of the blood test values? Any suggestions?

And another good thing is that he turn on and turn off the Tv and computer.He is always attentive to every conversation,we notice about it.

Next week I will give you another report as I promised

We really miss all of you and love you.

Best Regards from Uruguay

Jorge Pablo,Claudia and Sebastian

Date: 2014-06-29

Our Beloved Friends in Beijing.!!!(Dr Wu,Dr Wang,Dr Peng,Dr Susan Chu and Lisa)

Happy Weekend.!!!

Today,Saturday Night ,I decide to write you and send to you the blood test again to check.!!!And I add another picture of Sebastion doing excercise.The therapist works a lot with the right leg and with Sebastin back,so you can see the position of Sebastian in this picture.

You must know,that today,in the morning he ask me for his breakfast and told me:" Hurry up,I want to eat" and another word he says now is "goal" because of The World Cup.!!!

We can see everyday that he wants to do more things and he wants to show us that he can do.!!!We are very happy for that.!!!

I hope all of you are very well everyday,this is my wish,our wish.!!!

God bless all of you.!!!

We really love you and you know it.!!!

Jorge Pablo,Claudia and Sebastian


 Date: 2014-09-15

Hello Dear Lisa and Dr Susan Chu
 
How are you?I hope you are very well and here we are very well too!!!
 
This week we will send a new blood test.Sebastián is very well and his sense of houmour is good.
 
Now I´m writing to you to ask for medicine to Sebastián.Remember he will finish the next november but we must send the money through bank transfer and you must need time to send us.


Thank you very much for everything you do and the best wishes.!
 
God bless you.!!!

Date: 2014-09-18

Hi My Dears Friends ,Our Friends in Beijing...!
 
 How are you ?


Now I′m sending a new blood test.!
 
Please,try to indicate what can we do.We have gave medicine (T4) before breakfast as have indicated Dr Peng.
 
The teacher of Sebastián at the school, told me that he has a good behaviour,always smiles and she see that he is more concentrate than last year.She also told me that he wants to talk more and plays with other things.
 
I told her(the teacher) that Sebastián spends  more time standing looking at the Windows,right,and greeting people.!!!
 
He continues doing excercises,drawing,painting,eating all and plays with a notebook that have received from the school. I can see a good sense of humour.!
 
The Orthopedic surgeon ordered a plate of hip and back and  Neurosurgeon also called a CT brain to control.
 
We need another thing and favor from you:


Please,send Us a new list of the medicine without Sylimarin and Risperidone because we have got them.
 
We need the new list with the price and send the number of the account to do the bank transfer the next week,okey?


THANK YOU VERY MUCH FOR EVERYTHING
 
LOVES FROM URUGUAY...BECAUSE ALL OF YOU ARE IN OUR HEARTS.!!!


Jorge Pablo,Claudia and Sebastián

Date: 2014-09-27

Subject: Sebastián doing excercises everyday!!!Tired... but always doing them.!!! And More.!!!
 
Hello My Friends!Our Friends in Beijing.!!!
 
Here I´m sending a copy of a very short video that I have taken  today of Sebastián while he was doing the exercises.!It´s very short but I want to share with all of you.!
 
Please,don´t forget to tell me when you had received the confirmation of the bank transfer for medicine to Sebastián.! And give it  to my friend Juan Godoy.!Many Thanks.!!!

Here in Uruguay the spring is coming and we are very happy for this.We think everyday in all of you and we miss everytime too.
 
We have the best wishes for all of you and we loves too.!!!
 
I have a pray for you in our hearts.!!!


Jorge Pablo,Claudia and Sebastián Daniel Miranda
 

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