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Muhammad Ishtiaq Akram-Myositis-(Pakistan)-Posted on Dec.26th, 2017

Author Zhangqi Views Posted at 2017/12/26

Name: Muhammad Ishtiaq Akram
Sex: Male
Nationality: Pakistani
Age: 46Y
Diagnosis:Myositis
Date of Admission: August 4th, 2017
Treatment hospital/period: Wu Medical Center/14 days

Before treatment:
The patient did some tests 19 years ago as he felt weakness in his legs and fell down a lot. 17 years ago he also felt pain in his muscles  so he went to a local hospital and did a muscle biopsy. He was prescribed steroid 6 mg tid to treat the condition, he felt better and used it for 3 years. He was able to walk and drive 14 years ago but he was unable to run. His disease became worse and worse. 12 years ago he was able to walk but unable to stand up from a chair. He was diagnosed with myositis in 2015. At present he is able to walk but sometimes he needs help. It is difficult for him to change position.
His spirit, diet and sleep are normal. His urination and defecation functions are normal.

Admission PE:
Bp: 147/89mmHg, Hr: 83/min, body temperature: 36.5 degrees. Nutrition status is normal with normal physical development. There is no injury or bleeding spots of his skin and mucosa, no blausucht, slight throat congestion. Chest development is normal, the respiratory sounds in both lungs were clear with no dry or moist rales. The heart beat is powerful with regular cardiac rhythm and no obvious murmur in the valves. The abdomen was soft and bulging with no masses or tenderness. The liver and spleen were normal, no edema in the legs.

Nervous System Examination:
Patient was alert and his mental status was good. He displayed clear speech, and the memory, orientation and calculation abilities were normal. Both pupils were equal in size and round, diameter as 3.0 mm, react well to light and the eyeballs can move freely. Bilateral forehead wrinkle is symmetrical. The bilateral nasolabial groove depth is equal, tongue is in middle position,  showing the teeth is normal, he can bulge the cheeks as normal, chewing ability is normal and the soft palate can lift as normal. His hearing ability was normal. He could turn his neck and shrug powerfully. Muscle power of the right arm proximal side was 3 degrees, of distal side 4 degrees. Left arm proximal side muscle power was 3 degrees, distal side was 5 degrees. Muscle power of the legs was 2+ degrees. Muscle tone of all 4 limbs were normal. Bilateral biceps reflex were induced, the radial periosteal reflex and triceps reflex were normal. The patellar tendon reflex and Achilles tendon reflex could not be induced by examination. Bilateral Palm-jaw reflex, Rossilimo sign, sucking reflex and Hoffmann sign were negative. Babinski sign of both sides were negative. Sensory examination was normal. Finger to nose test, the finger opposite movement and fast alternate movement were normal. He could not perform the Heel-knee-tibia test because of the weakness. The Romberg's sign was doubtful positive. He could not stand with one leg. The Meningeal irritation sign was negative.

Treatment:
After the admission he received related examinations and this confirmed the prior diagnosis. He received 3 neural stem cell injections and 3 mesenchymal stem cell injections to repair his damaged muscle cells, replace dead cells with new injected stem cells, nourish cells, regulate his immune system and improve blood circulation. This was done with rehabilitation training.     

Post-treatment:
After 14 days’ treatment his muscle pain decreased. The muscle power of the arms was  better with the muscle power of the proximal side now 4- degrees. The muscle power of his legs increased also. He could now change his body position much easier.

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